Usually means: Membrane-bound organelle storing substances.
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We found 31 dictionaries that define the word vacuole:

General (21 matching dictionaries)
  1. vacuole: Merriam-Webster
  2. vacuole: Oxford Learner's Dictionaries
  3. vacuole: American Heritage Dictionary of the English Language
  4. vacuole: Collins English Dictionary
  5. vacuole: Vocabulary.com
  6. vacuole: Wordnik
  7. vacuole: Cambridge Advanced Learner's Dictionary
  8. Vacuole: InfoVisual Visual Dictionary
  9. vacuole: Wiktionary
  10. vacuole: Webster's New World College Dictionary, 4th Ed.
  11. vacuole: The Wordsmyth English Dictionary-Thesaurus
  12. vacuole: Infoplease Dictionary
  13. vacuole: Dictionary.com
  14. Vacuole: Wikipedia, the Free Encyclopedia
  15. Vacuole: Online Plain Text English Dictionary
  16. vacuole: Webster's Revised Unabridged, 1913 Edition
  17. vacuole: Rhymezone
  18. Vacuole: AllWords.com Multi-Lingual Dictionary
  19. vacuole: FreeDictionary.org
  20. vacuole: Mnemonic Dictionary
  21. vacuole: TheFreeDictionary.com

Computing (1 matching dictionary)
  1. vacuole: Encyclopedia

Medicine (5 matching dictionaries)
  1. vacuole: Merriam-Webster Medical Dictionary
  2. Dorland's Illustrated Medical Dictionary (No longer online)
  3. online medical dictionary (No longer online)
  4. DICTIONARY OF TERMS IN ORAL PHYSIOLOGY (No longer online)
  5. vacuole: Medical dictionary

Science (4 matching dictionaries)
  1. Drug Discovery and Development (No longer online)
  2. Botanical Terms (No longer online)
  3. Tree of Life Glossary (No longer online)
  4. vacuole: Natural History Terms

(Note: See vacuolar as well.)

Definitions from Wiktionary (vacuole)

noun:  (cytology) A large membrane-bound vesicle in a cell's cytoplasm.
noun:  A small empty or air-filled space or vacuity.

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