Usually means: Genetically distinct subgroup within population.
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We found 6 dictionaries that define the word subclone:

General (2 matching dictionaries)
  1. subclone: Wiktionary
  2. subclone: Dictionary.com

Medicine (3 matching dictionaries)
  1. subclone: Merriam-Webster Medical Dictionary
  2. Dorland's Illustrated Medical Dictionary (No longer online)
  3. subclone: Medical dictionary

Science (1 matching dictionary)
  1. Drug Discovery and Development (No longer online)

Definitions from Wiktionary (subclone)

noun:  (genetics) A clone or descendant of a mutant occurring in a previous clone
noun:  (genetics, molecular biology) A partial segment of DNA, cloven from a previously-cloned segment, which is then cloned into another vector
verb:  (genetics) To reclone part of a previously-cloned DNA segment into a new vector

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