Usually means: Breeding within the same breed.
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We found 4 dictionaries that define the word straightbred:

General (3 matching dictionaries)
  1. straightbred: Merriam-Webster.com
  2. straightbred: Collins English Dictionary
  3. straightbred: Wiktionary

Medicine (1 matching dictionary)
  1. straightbred: Medical dictionary

Definitions from Wiktionary (straightbred)

adjective:  Produced by breeding from a single breed, variety or species.
noun:  Any organism produced by breeding from a single breed, variety, or species.

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