Usually means: Temporary obstacle hindering progress, achievement.
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We found 38 dictionaries that define the word setback:

General (24 matching dictionaries)
  1. setback: Longman Dictionary of Contemporary English
  2. setback: Merriam-Webster
  3. setback: Oxford Learner's Dictionaries
  4. setback: American Heritage Dictionary of the English Language
  5. setback: Collins English Dictionary
  6. setback: Vocabulary.com
  7. Setback, setback: Wordnik
  8. setback: Cambridge Advanced Learner's Dictionary
  9. setback: Wiktionary
  10. setback: Webster's New World College Dictionary, 4th Ed.
  11. setback: The Wordsmyth English Dictionary-Thesaurus
  12. setback: Dictionary.com
  13. setback: Cambridge Essential American English Dictionary
  14. Setback (architecture), Setback (card game), Setback (land use), Setback: Wikipedia, the Free Encyclopedia
  15. Setback: Online Plain Text English Dictionary
  16. setback: Webster's Revised Unabridged, 1913 Edition
  17. setback: Rhymezone
  18. setback: AllWords.com Multi-Lingual Dictionary
  19. setback: FreeDictionary.org
  20. setback: Mnemonic Dictionary
  21. setback: TheFreeDictionary.com
  22. setback: Wikimedia Commons US English Pronunciations

Business (6 matching dictionaries)
  1. MoneyGlossary.com (No longer online)
  2. setback: Webster's New World Law Dictionary
  3. Everybody's Legal Dictionary (No longer online)
  4. setback: Legal dictionary
  5. setback: Financial dictionary
  6. BusinessDictionary.com (No longer online)

Computing (1 matching dictionary)
  1. setback: Encyclopedia

Medicine (2 matching dictionaries)
  1. online medical dictionary (No longer online)
  2. setback: Medical dictionary

Miscellaneous (1 matching dictionary)
  1. setback: Idioms

Slang (1 matching dictionary)
  1. setback: Urban Dictionary

Sports (2 matching dictionaries)
  1. Setback: Card Games
  2. Setback: Bicycle Glossary

Tech (1 matching dictionary)
  1. Explosives (No longer online)

(Note: See setbacks as well.)

Definitions from Wiktionary (
)
American English Definition British English Definition
noun:  An obstacle, delay, disadvantage, or blow (an adverse event which slows down, or prevents progress towards a desired outcome).
noun:  (by extension) Any adverse event, defeat, or impediment of progress.
noun:  (US) The required distance between a structure and a road.
noun:  (architecture) A step-like recession in a wall.
noun:  An offset to the temperature setting of a thermostat to cover a period when more or less heating is required than usual.
noun:  (possibly archaic) A backset; a countercurrent; an eddy.
noun:  (archaic) A backset; a check; a repulse; a relapse.

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