Sorry, no online dictionaries contain the exact phrase response-surface methodology.
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Reverse dictionary results:
1. approach
 2. approaches
3. basis
4. manner
5. means
6. method
7. methodological
8. methodologies
9. methods
10. mode
 11. practices
12. procedure
13. procedures
14. process
15. processes
16. system
17. techniques
18. ways
19. eras
20. adopted
 21. analytic
22. cartesian
23. commercialize
24. dressage
25. hermeneutics
26. historiography
27. how
28. hpc
29. methodologically
30. methodologist
 31. optimization
32. politics
33. pseudoscience
34. scholasticism
35. scientific
36. skepticism
37. technical
38. valuation
39. value analysis
40. amnesic

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