Sorry, no online dictionaries contain the exact phrase profoundly meaningful.
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Reverse dictionary results:
1. deep
2. awed
3. awful
4. deeply
5. especially
6. heartfelt
7. incredible
8. intellect
9. intense
10. mainly
11. mostly
12. obese
13. poignant
14. prodigious
15. sacred
16. sage
17. shape
18. soulful
19. wretched
20. absolute
21. crack
22. effectively
23. enriching
24. expression
25. eye
26. heavy
27. helpful
28. important
29. inane
30. interesting
31. larger
32. largest
33. pregnant
34. rich
35. sense
36. significant
37. significantly
38. stronger
39. substantive
40. tich

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