Sorry, no online dictionaries contain the exact phrase make something different.
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Reverse dictionary results:
1. alter
2. change
3. modify
4. transform
5. adjust
6. altering
7. changer
8. convert
9. modification
10. modified
11. mutate
12. permutate
13. amend
14. amended
15. conversion
16. mod
17. modulate
18. mutandum
19. translate
20. update
21. adjustment
22. changing
23. chg
24. evolve
25. subsample
26. transmutation
27. transmute
28. adjusting
29. alteration
30. distribution
31. edit
32. edited
33. morph
34. transition
35. transmutate

You can look up the words in the phrase individually using these links:   make ?   something ?   different ?
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