Sorry, no online dictionaries contain the exact phrase main problem.
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Reverse dictionary results:
1. issue
2. challenge
3. obstacle
4. concern
5. complication
6. proceeder
7. ambition
8. entent
9. exhort
10. impetrative
11. interest
12. persuader
13. countenancer
14. encourage
15. enterest
16. exceptant
17. implorer
18. matter
19. prospecting
20. affecter
21. attendance
22. compel
23. compulsory
24. exhorter
25. impetrate
26. incent
27. inviteth
28. obleeged
29. obligatory
30. succedane
31. tractation
32. adhortation
33. adjurer
34. amercer
35. beckoner
36. cautioner
37. cautionry
38. coact
39. compromiser

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You can look up the words in the phrase individually using these links:   main ?   problem ?
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