Usually means: Informal term for quaalude sedative.
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We found 14 dictionaries that define the word lude:

General (11 matching dictionaries)
  1. lude: Merriam-Webster.com
  2. lude: American Heritage Dictionary of the English Language
  3. lude: Collins English Dictionary
  4. Lude, lude: Wordnik
  5. lude: Wiktionary
  6. lude: Webster's New World College Dictionary, 4th Ed.
  7. lude: The Wordsmyth English Dictionary-Thesaurus
  8. lude: Infoplease Dictionary
  9. lude: Dictionary.com
  10. Lude: Wikipedia, the Free Encyclopedia
  11. lude: Dictionary/thesaurus

Medicine (1 matching dictionary)
  1. lude: Medical dictionary

Slang (2 matching dictionaries)
  1. lude: Green’s Dictionary of Slang
  2. lude: Urban Dictionary

Definitions from Wiktionary (lude)

noun:  (slang) A pill containing the drug methaqualone.
verb:  (slang, intransitive) To get high on Quaalude.

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