Usually means: Favors using left hand primarily.
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We found 32 dictionaries that define the word left-handed:

General (24 matching dictionaries)
  1. left-handed: Merriam-Webster.com
  2. left-handed: Oxford Learner's Dictionaries
  3. left-handed: American Heritage Dictionary of the English Language
  4. left-handed, left-handed: Collins English Dictionary
  5. left-handed: Vocabulary.com
  6. Left-Handed, Left-handed, left-handed: Wordnik
  7. left-handed: Cambridge Advanced Learner's Dictionary
  8. left-handed: Wiktionary
  9. left-handed: Webster's New World College Dictionary, 4th Ed.
  10. left-handed: The Wordsmyth English Dictionary-Thesaurus
  11. left-handed: Infoplease Dictionary
  12. Left-handed, left-handed: Dictionary.com
  13. left-handed: Cambridge Essential American English Dictionary
  14. Left-handed: Wikipedia, the Free Encyclopedia
  15. Left-handed: Online Plain Text English Dictionary
  16. left-handed: Webster's Revised Unabridged, 1913 Edition
  17. left-handed: Rhymezone
  18. left-handed: AllWords.com Multi-Lingual Dictionary
  19. left-handed: Webster's 1828 Dictionary
  20. left-handed: Free Dictionary
  21. left-handed: Mnemonic Dictionary
  22. left-handed: Dictionary/thesaurus

Computing (1 matching dictionary)
  1. left-handed: Encyclopedia

Medicine (4 matching dictionaries)
  1. online medical dictionary (No longer online)
  2. left-handed: Medical dictionary
  3. Left-handed: Drug Medical Dictionary
  4. Left-handed: MedTerms.com Medical Dictionary

Religion (1 matching dictionary)
  1. Left-handed: Easton Bible

Slang (2 matching dictionaries)
  1. left-handed: Green’s Dictionary of Slang
  2. left-handed: Urban Dictionary

(Note: See left-handedly as well.)

Definitions from Wiktionary (
)
American English Definition British English Definition
adjective:  Using one's left hand in preference to, or more skillfully than, one's right.
adjective:  Intended to be worn on, or used by, the left hand.
adjective:  Turning or spiraling from right to left; anticlockwise.
adjective:  Awkward or maladroit.
adjective:  Insincere or malicious.
adjective:  (occult, of magic) Performed with the intention of doing harm or in transgression against convention or taboo; following the left-hand path
adjective:  Of a coordinate system: not following the right-hand rule.
noun:  Left-handed people, taken as a whole.

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