Sorry, no online dictionaries contain the exact phrase large-scale science.
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Reverse dictionary results:
1. major
 2. comprehensive
3. general
4. generalized
5. gross
6. high
7. important
8. key
9. magnitude
10. micro
 11. scale
12. ambitious
13. across-the-board
14. ample
15. big
16. blow-up
17. broad
18. broad-based
19. bulk
20. bulky
 21. colossal
22. considerable
23. daunting
24. drastic
25. enormous
26. extensive
27. far-reaching
28. forklift
29. full-blown
30. full-scale
 31. full-sized
32. giant
33. gigantic
34. grand
35. grande
36. grandes
37. grandi
38. great
39. heavy
40. high-profile

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You can look up the words in the phrase individually using these links:   large-scale ?   science ?
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Not helpful? You might try using the wildcards * and ? to find the word you're looking for. For example, use
larg*to search for words beginning with larg, or
*enceto search for words ending with ence
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