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We found one dictionary that defines the word imperial disease:

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  1. imperial disease: Wiktionary

Definitions from Wiktionary (imperial disease)

noun:  A disease that arises from colonial exploration and causes significant harm to an empire, especially the British Empire.
noun:  (by extension) A failing to which an empire is prone.
noun:  A communicable disease that is spread to indigenous people by conquering imperial forces.

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