Usually means: Severe dehydration causing extreme hyperglycemia.
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We found 3 dictionaries that define the word hyperosmolar coma:

General (1 matching dictionary)
  1. hyperosmolar coma: Wiktionary

Medicine (2 matching dictionaries)
  1. Hyperosmolar Coma: Diabetes Dictionary
  2. Hyperosmolar coma: Medical dictionary

Definitions from Wiktionary (hyperosmolar coma)

noun:  Any coma that results from a greater than normal amount of glucose in the blood

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