We found one dictionary that defines the word gone off the reservation:

General (1 matching dictionary)

1. gone off the reservation: Wiktionary

▸ Words similar to gone off the reservation ▸ Usage examples for gone off the reservation ▸ Idioms related to gone off the reservation ▸ Wikipedia articles (New!) ▸ Words that often appear near gone off the reservation ▸ Rhymes of gone off the reservation ▸ Invented words related to gone off the reservation