Usually means: Large-scale reduction in population.
Definitions Related words Mentions
We found 17 dictionaries that define the word die off:

General (16 matching dictionaries)
  1. die-off, die off: Merriam-Webster.com
  2. die-off, die off: Oxford Learner's Dictionaries
  3. die-off: American Heritage Dictionary of the English Language
  4. die-off, die-off, die off: Collins English Dictionary
  5. die off: Vocabulary.com
  6. Die-Off, Die-off, die-off: Wordnik
  7. die off: Cambridge Advanced Learner's Dictionary
  8. die-off, die off: Wiktionary
  9. die-off: Infoplease Dictionary
  10. die-off, die off: Dictionary.com
  11. die off: Rhymezone
  12. die off: Free Dictionary
  13. die off: Mnemonic Dictionary
  14. die-off, die off: Dictionary/thesaurus

Miscellaneous (1 matching dictionary)
  1. die off: Idioms

(Note: See die_offs as well.)

Definitions from Wiktionary (die off)

verb:  To suffer a series of deaths; to die one by one; to progressively become extinct. (If a group of plants, animals, or people dies off, the entire group dies over a period of time.)
verb:  To become defunct or nonexistent.
verb:  Of music, noise, etc., to reduce in volume until no longer audible.

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