Usually means: Leave from a starting point.
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We found 33 dictionaries that define the word depart:

General (26 matching dictionaries)
  1. depart: Merriam-Webster.com
  2. depart: Oxford Learner's Dictionaries
  3. depart: American Heritage Dictionary of the English Language
  4. depart: Collins English Dictionary
  5. depart: Vocabulary.com
  6. Depart, depart: Wordnik
  7. depart: Cambridge Advanced Learner's Dictionary
  8. depart: Wiktionary
  9. depart: Webster's New World College Dictionary, 4th Ed.
  10. depart: The Wordsmyth English Dictionary-Thesaurus
  11. depart: Infoplease Dictionary
  12. Depart, depart: Dictionary.com
  13. depart: Online Etymology Dictionary
  14. depart: Cambridge Essential American English Dictionary
  15. Depart: Online Plain Text English Dictionary
  16. depart: Webster's Revised Unabridged, 1913 Edition
  17. depart: Rhymezone
  18. depart: AllWords.com Multi-Lingual Dictionary
  19. depart: Webster's 1828 Dictionary
  20. Depart: Dictionary of Phrase and Fable (1898)
  21. depart: Free Dictionary
  22. depart: Mnemonic Dictionary
  23. depart: Dictionary/thesaurus
  24. depart: Wikimedia Commons US English Pronunciations

Art (2 matching dictionaries)
  1. Shakespeare Glossary (No longer online)
  2. Natural Magick (No longer online)

Business (1 matching dictionary)
  1. depart: Legal dictionary

Computing (1 matching dictionary)
  1. depart: Encyclopedia

Medicine (1 matching dictionary)
  1. online medical dictionary (No longer online)

Miscellaneous (2 matching dictionaries)
  1. Navajo Code Talkers' Dictionary (No longer online)
  2. depart: Idioms

(Note: See departed as well.)

Definitions from Wiktionary (
)
American English Definition British English Definition
verb:  (intransitive) To leave.
verb:  (intransitive) To set out on a journey.
verb:  (intransitive, euphemistic) To die.
verb:  (intransitive, figurative) To disappear, vanish; to cease to exist.
verb:  (intransitive) To deviate (from), be different (from), fail to conform.
verb:  (transitive) To go away from; to leave.
verb:  (transitive, intransitive, aviation) To lose control of an aircraft; to "depart" (sense 5) from controlled flight (with the aircraft as the direct object)
verb:  (obsolete, transitive) To divide up; to distribute, share.
verb:  (obsolete, transitive) To separate, part.
noun:  (obsolete) Division; separation, as of compound substances.
noun:  (obsolete) A going away; departure.

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