Definitions from Wiktionary (defame)

▸ verb:  To disgrace; to bring into disrepute.
▸ verb:  (now chiefly historical) To charge; to accuse (someone) of an offence.
▸ verb:  To harm or diminish the reputation of; to disparage.
▸ noun:  (now rare, archaic) Disgrace, dishonour.
▸ noun:  (now rare or nonstandard) Defamation; slander, libel.
▸ adjective:  (heraldry) Synonym of defamed
▸ Also see defame

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