We found 2 dictionaries that define the word be up and running:

General (1 matching dictionary)

1. be up and running: ESL Idiom Page

Miscellaneous (1 matching dictionary)

2. be up and running: Idioms

▸ Words similar to be up and running ▸ Usage examples for be up and running ▸ Idioms related to be up and running ▸ Wikipedia articles (New!) ▸ Words that often appear near be up and running ▸ Rhymes of be up and running ▸ Invented words related to be up and running