Usually means: Surgical removal of reproductive organs.
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We found 32 dictionaries that define the word SPAY:

General (25 matching dictionaries)
  1. spay: Merriam-Webster.com
  2. spay: Oxford Learner's Dictionaries
  3. spay: American Heritage Dictionary of the English Language
  4. spay: Collins English Dictionary
  5. spay: Vocabulary.com
  6. Spay, spay: Wordnik
  7. spay: Cambridge Advanced Learner's Dictionary
  8. spay: Wiktionary
  9. spay: Webster's New World College Dictionary, 4th Ed.
  10. spay: The Wordsmyth English Dictionary-Thesaurus
  11. spay: Infoplease Dictionary
  12. spay: Dictionary.com
  13. spay: Online Etymology Dictionary
  14. spay: Cambridge Essential American English Dictionary
  15. Spay (disambiguation), Spay: Wikipedia, the Free Encyclopedia
  16. Spay: Online Plain Text English Dictionary
  17. spay: Webster's Revised Unabridged, 1913 Edition
  18. spay: Rhymezone
  19. spay: AllWords.com Multi-Lingual Dictionary
  20. spay: Webster's 1828 Dictionary
  21. spay: Free Dictionary
  22. spay: Mnemonic Dictionary
  23. spay: Dictionary/thesaurus

Computing (1 matching dictionary)
  1. spay: Encyclopedia

Medicine (3 matching dictionaries)
  1. Dorland's Illustrated Medical Dictionary (No longer online)
  2. online medical dictionary (No longer online)
  3. spay: Medical dictionary

Miscellaneous (1 matching dictionary)
  1. Glossary of Unusual Sexual Practices (No longer online)

Slang (1 matching dictionary)
  1. spay: Urban Dictionary

Sports (1 matching dictionary)
  1. Cat Terms (No longer online)

(Note: See spayed as well.)

Definitions from Wiktionary (spay)

verb:  (transitive) To destroy or remove the ovaries and/or uterus (of a female animal) to prevent pregnancy.
noun:  The act of spaying an animal.
noun:  Rare spelling of spayard. [(obsolete) The hart in its third year; a young deer]
verb:  Alternative form of spae (to foretell or divine) [(Scotland) To divine; foretell.]

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