Usually means: Cause annoyance or discomfort repeatedly.
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We found 33 dictionaries that define the word Irritate:

General (27 matching dictionaries)
  1. irritate: Merriam-Webster
  2. irritate: Oxford Learner's Dictionaries
  3. irritate: American Heritage Dictionary of the English Language
  4. irritate: Collins English Dictionary
  5. irritate: Vocabulary.com
  6. Irritate, irritate: Wordnik
  7. irritate: Cambridge Advanced Learner's Dictionary
  8. irritate: Wiktionary
  9. irritate: Webster's New World College Dictionary, 4th Ed.
  10. irritate: The Wordsmyth English Dictionary-Thesaurus
  11. irritate: Infoplease Dictionary
  12. irritate: Dictionary.com
  13. irritate: Online Etymology Dictionary
  14. irritate: Cambridge Essential American English Dictionary
  15. Irritate: Wikipedia, the Free Encyclopedia
  16. Irritate: Online Plain Text English Dictionary
  17. irritate: Webster's Revised Unabridged, 1913 Edition
  18. irritate: Rhymezone
  19. irritate: AllWords.com Multi-Lingual Dictionary
  20. irritate: Webster's 1828 Dictionary
  21. irritate: FreeDictionary.org
  22. irritate: Mnemonic Dictionary
  23. irritate: TheFreeDictionary.com
  24. irritate: Wikimedia Commons US English Pronunciations
  25. irritate: Longman Dictionary of Contemporary English

Business (1 matching dictionary)
  1. irritate: Legal dictionary

Computing (1 matching dictionary)
  1. irritate: Encyclopedia

Medicine (3 matching dictionaries)
  1. irritate: Merriam-Webster Medical Dictionary
  2. online medical dictionary (No longer online)
  3. irritate: Medical dictionary

Slang (1 matching dictionary)
  1. Irritate: Urban Dictionary

(Note: See irritated as well.)

Google, News, Images, Wikipedia, Reddit, Scrabble
Definitions from Wiktionary (irritate)

▸ verb:  (transitive) To provoke impatience, anger, or displeasure in.
▸ verb:  (intransitive) To cause or induce displeasure or irritation.
▸ verb:  (transitive) To induce pain in (all or part of a body or organism).
▸ verb:  (transitive, obsolete, Scots law) To render null and void.

Similar:
bother, annoy, vex, rile, rag, nark, get at, get to, gravel, devil, more...

Opposite:
soothe, calm, relax

Types:
chafe, bother, bug, burn, goad, grate, harry, nettle, pique, more...

Phrases:
How to Irritate People, irritate or damage by rubbing, slightly irritate, annoy or irritate, irritate by rubbing, more...

Colors:
    red,     neon green,     bright yellow,     orange,     magenta, more...


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Similar:
bother, annoy, vex, rile, rag, nark, get at, get to, gravel, devil, more...

Opposite:
soothe, calm, relax

Types:
chafe, bother, bug, burn, goad, grate, harry, nettle, pique, more...

Phrases:
How to Irritate People, irritate or damage by rubbing, slightly irritate, annoy or irritate, irritate by rubbing, to irritate, irritate no end, irritate repeated, to irritate annoy provoke, more...

Colors:
    red,     neon green,     bright yellow,     orange,     magenta, more...



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