Usually means: High-performance computing, powerful computational capabilities.
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We found 13 dictionaries that define the word HPC:

General (5 matching dictionaries)
  1. hpc: Wordnik
  2. HPC: Wiktionary
  3. HPC: Dictionary.com
  4. HPC, Hpc: Wikipedia, the Free Encyclopedia
  5. HPC: Stammtisch Beau Fleuve Acronyms

Computing (2 matching dictionaries)
  1. Webopedia (No longer online)
  2. HPC: Encyclopedia

Miscellaneous (2 matching dictionaries)
  1. HPC: Acronym Finder
  2. AbbreviationZ (No longer online)

Science (1 matching dictionary)
  1. HPC: Cytokines & Cells Online Pathfinder Encyclopaedia

Slang (1 matching dictionary)
  1. HPC: Urban Dictionary

Tech (2 matching dictionaries)
  1. AUTOMOTIVE TERMS (No longer online)
  2. National Weather Service Glossary (No longer online)

Definitions from Wiktionary (HPC)

noun:  (computing) Initialism of high-performance computing.
noun:  (organic chemistry) Initialism of hydroxypropyl cellulose. [(organic chemistry) A derivative of cellulose with both water solubility and organic solubility. Used as an excipient and food ingredient.]
noun:  (electricity, automotive) Initialism of high power charging.

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