Usually means: Complex Instruction Set Computer architecture.
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We found 27 dictionaries that define the word CISC:

General (13 matching dictionaries)
  1. CISC: Merriam-Webster
  2. CISC: American Heritage Dictionary of the English Language
  3. CISC: Vocabulary.com
  4. CISC: Wiktionary
  5. CISC: Infoplease Dictionary
  6. CISC: Dictionary.com
  7. CISC, Cisc: Wikipedia, the Free Encyclopedia
  8. Cisc: Rhymezone
  9. CISC: Stammtisch Beau Fleuve Acronyms
  10. cisc: FreeDictionary.org
  11. cisc: Mnemonic Dictionary
  12. CISC: TheFreeDictionary.com
  13. CISC: Merriam-Webster

Computing (7 matching dictionaries)
  1. CISC: Free On-line Dictionary of Computing
  2. BABEL: Computer Oriented Abbreviations and Acronyms (No longer online)
  3. CISC: Tech Terms Computer Dictionary
  4. CISC (Complex Instruction Set Computer): Linktionary Networking Glossary
  5. Webopedia (No longer online)
  6. I T Glossary (No longer online)
  7. CISC: Encyclopedia

Medicine (2 matching dictionaries)
  1. online medical dictionary (No longer online)
  2. University of Maryland Glossary of Medical Terms (No longer online)

Miscellaneous (2 matching dictionaries)
  1. CISC: Acronym Finder
  2. AbbreviationZ (No longer online)

Slang (1 matching dictionary)
  1. CISC: Urban Dictionary

Tech (2 matching dictionaries)
  1. Rane Professional Audio Reference (No longer online)
  2. Sweetwater Music (No longer online)

Definitions from Wiktionary (CISC)

noun:  (computing, retronym) Acronym of complex instruction set computer.

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