Usually means: Informal term for application software.
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We found 10 dictionaries that define the word appy:

General (6 matching dictionaries)
  1. Appy: Merriam-Webster.com
  2. Appy, appy: Wordnik
  3. 'appy, appy: Wiktionary
  4. APPY, appy: Dictionary.com
  5. Appy: Wikipedia, the Free Encyclopedia
  6. Appy: Merriam-Webster.com

Medicine (1 matching dictionary)
  1. Hepatitis C Information Central (No longer online)

Miscellaneous (1 matching dictionary)
  1. Appy: Acronym Finder

Slang (2 matching dictionaries)
  1. appy: Green’s Dictionary of Slang
  2. appy: Urban Dictionary

Definitions from Wiktionary (appy)

noun:  (informal) An appetizer.
noun:  (medicine, colloquial, slang) Appendix.
noun:  (medicine, colloquial, slang) Appendicitis.
noun:  (medicine, colloquial, slang) Appendectomy.

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