Concept cluster: Drugs > TKIs
n
(pharmacology) An antineoplastic cyclin-dependent kinase inhibitor used to treat breast cancer.
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(pharmacology) A leukotriene antagonist used in the treatment of inflammatory skin conditions.
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A form of paclitaxel combined with an albumin
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(pharmacology) A retinoid that is used to treat psoriasis.
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An inhibitor of insulin receptor substrate (IRS)-1 expression.
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An orally available selective aurora A kinase inhibitor being investigated as a treatment for relapsed or refractory peripheral T-cell lymphoma.
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(pharmacology) A synthetic muramyl dipeptide analogue with potential immunostimulating and antineoplastic activity.
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Nilotinib.
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The pharmaceutical drug N-[(E)-(3-methylphenyl)methylideneamino]-6-morpholin-4-yl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine
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A protein kinase inhibitor used to treat Philadelphia chromosome-positive chronic myeloid leukemia.
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A drug used to treat some lymphomas
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A small-molecule tyrosine kinase inhibitor.
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(medicine) A kinase inhibitor used to combat rheumatoid arthritis (and possibly COVID-19)
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An interferon used to treat multiple sclerosis
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A pharmaceutical drug for the treatment of ovarian cancer.
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A drug for the treatment of certain lung cancers.
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(medicine) A mitogen-activated protein kinase inhibitor used, in combination with vemurafenib to treat melanoma
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(medicine) conventional synthetic disease-modifying antirheumatic drug
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Alternative form of ciclosporin. [(pharmacology) An immunosuppressive drug C₆₂H₁₁₁N₁₁O₁₂ that is a cyclic polypeptide obtained as a metabolite from a fungus (Tolypocladium inflatum) and is used especially to prevent rejection of transplanted organs and in the treatment of rheumatoid arthritis and psoriasis.]
n
(pharmacology) Alternative form of ciclosporin. [(pharmacology) An immunosuppressive drug C₆₂H₁₁₁N₁₁O₁₂ that is a cyclic polypeptide obtained as a metabolite from a fungus (Tolypocladium inflatum) and is used especially to prevent rejection of transplanted organs and in the treatment of rheumatoid arthritis and psoriasis.]
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A drug for the treatment of cancers associated with a mutated version of the gene BRAF.
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An experimental drug candidate under development for the treatment of non-small-cell lung carcinoma.
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A particular therapeutic interleukin.
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A mitogen-activated protein kinase inhibitor.
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A novel inhibitor of PI3K delta and gamma, used to treat hematologic malignancies and inflammatory conditions.
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(pharmacology) A synthetic peptide that is used to treat cases of lupus.
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A drug for the treatment of chemotherapy-induced neutropenia.
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A particular drug that is an inhibitor of the enzyme spleen tyrosine kinase (Syk).
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(pharmacology) An anticoagulant drug.
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A drug, used in the treatment of certain types of cancer, that acts in a similar way to erlotinib by selectively targeting the mutant proteins in malignant cells.
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A targeted covalent inhibitor of Bruton's tyrosine kinase and hence used in treating B cell malignancies.
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A particular drug for the treatment of chronic lymphocytic leukemia.
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A tyrosine kinase inhibitor structurally related to staurosporine.
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A tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals.
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The drug osimertinib.
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A drug being investigated for the treatment of acute myeloid leukemia and myelodysplastic syndrome.
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(pharmacology) A drug used to treat Fabry disease
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A tyrosine kinase inhibitor used to treat some cancers
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A drug being investigated as a treatment for cancer.
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A drug used to treat viral infections of the respiratory tract
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(pharmacology) An antitumour drug.
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A drug used to treat dermatitis in dogs.
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A mouse monoclonal antibody under investigation as a drug to prevent transplant rejection and to treat various immunological diseases.
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An anticancer medication used to treat relapsed or refractory acute myeloid leukemia.
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A drug used to treat breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
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A drug for the treatment of certain bile duct cancers.
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(pharmacology) A biological response modifier drug.
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(pharmacology) An investigational inhibitor of the protein mTOR (mammalian target of rapamycin).
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A particular interleukin 1 inhibitor.
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(medicine) An amino acid amide that inhibits the fibroblast growth factor
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(pharmacology) A particular Ras inhibitor.
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(medicine) A vaccine therapy used to treat some cancers
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activin inhibitor, trialled among other applications to counteract chemotherapy-induced anaemia
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(pharmacology) An immunosuppressive drug obtained from Streptomyces tsukubaensis used mainly after organ transplantation.
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(pharmacology) A dipeptidyl peptidase inhibitor.
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(pharmacology) A heat shock protein inhibitor that has some potential for treatment for multiple myeloma.
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An anticancer medication used to treat uveal melanoma.
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(pharmacology) An intravenous drug for the treatment of renal cell carcinoma, a derivative of sirolimus.
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(pharmacology) A human monoclonal antibody designed for the treatment of solid and hematologic tumours.
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An immunostimulant drug.
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An experimental anticancer drug that is activated to a toxic radical only at very low levels of oxygen.
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A recombinant form of human basic fibroblast growth factor (bFGF), used to treat skin ulcers.
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(pharmacology) A synthetic compound derived from cyclohexane which inhibits the breakdown of fibrin in blood clots and is used to treat hemorrhage.
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A particular drug that inhibits angiogenesis.
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A drug for the treatment of late-stage melanoma.
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(medicine) A drug used to treat leukemia
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(pharmacology) A drug that acts as a selective antagonist for the NK₁ receptor, under development as a potential antiemetic and anxiolytic and to treat tinnitus.
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A calcineurin inhibitor used as an immunosuppressant medication.
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A medication for the treatment of the polyneuropathy of hereditary transthyretin-mediated (hATTR) amyloidosis in adults.
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A trademarked name for the anti-cancer drug goserelin.
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A particular antitumor drug.

Note: Concept clusters like the one above are an experimental OneLook feature. We've grouped words and phrases into thousands of clusters based on a statistical analysis of how they are used in writing. Some of the words and concepts may be vulgar or offensive. The names of the clusters were written automatically and may not precisely describe every word within the cluster; furthermore, the clusters may be missing some entries that you'd normally associate with their names. Click on a word to look it up on OneLook.
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