n
(organic chemistry) The principal compound found in wormwood (Artemisia absinthium), having a bitter taste: C₁₅H₂₀O₄
n
(organic chemistry) Any of a class of antibiotic phenolic lactones, based on (2S,3S,4S)-4-amino-2,3-dihydroxy-N1-{(1S)-1-[(3S)-8-hydroxy-1-oxo-3,4-dihydro-1H-isochromen-3-yl]-3-methylbutyl}hexanediamide, produced by Bacillus pumilus
n
(organic chemistry) Any of a class of macrolides, isolated from marine dinoflagellates of the genus Amphidinium, that show antitumor activity.
n
(organic chemistry) Any of a group of ansamycin macrolides present in marine some bacteria
n
(organic chemistry) A macrolide that has some antitumour effects
n
(organic chemistry) A bitter resin that is an active principle of Arnica montana.
n
(organic chemistry) An experimental drug that may have some antimalarial activity
n
Any of a class of naphthopyrone mycotoxins obtained from Aspergillus molds
n
A macrolide derived from azadirachtin
n
(organic chemistry) Any of a group of antitumor antibiotics, based on (2S)-N-[(3S,4R,4aR,5R,6R)-3-(dichloromethyl)-5,6,8-trihydroxy-3-methyl-1-oxo-4a,5,6,7-tetrahydro-4H-isochromen-4-yl]-2-aminopropanamide, present in Pseudomonas
n
A psilocybin mushroom alkaloid and analog of psilocybin.
n
(organic chemistry) Any of a class of cyclic amides, isolated from various sponges, that have some anticancer activity
n
(organic chemistry) A lactam having a four-membered ring structure; a structural element of many antibiotics such as penicillin.
n
(organic chemistry) Any of a small group of cytotoxic cyclic peptides present in the marine sponge Discodermia calyx
n
Alternative form of camptothecin [(medicine) An alkaloid, derived from the tree Camptotheca acuminata, that inhibits DNA topomerase and is used as an anticancer drug]
n
(organic chemistry, medicine) Any of a group of antibiotics that have a uracil nucleoside structure with a caprolactam substituent
n
(organic chemistry) Any of a class of broad-spectrum beta-lactam antibiotics that are resistant to enzymatic hydrolysis
n
(organic chemistry) A degradation product of cephalosporin 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid
n
(organic chemistry) Any of a class of cyclodepsipeptide present in some bacteria
n
(organic chemistry) A cyclic octapeptide present in Streptomyces champavatii
n
(medicine) A complex epidithiodioxopiperazine metabolite, produced by several fungi of the genus Chaetomium, that disrupts the ability of tumours to adapt to hypoxia
n
(organic chemistry) A tetracyclic lantibiotic produced by Streptomyces cinnamoneus
n
(organic chemistry) A microbial terpenoid, related to clerodane, that stimulates DNA cleavage
n
(organic chemistry) A macrolide, present in the bacterium Streptomyces conglobatus, that may have antitumour activity
n
(organic chemistry) A antimycotic present in a fungus of the genus Cryptosporiopsis
n
Any of a class of oligopeptides produced by cyanobacteria.
n
(pharmacology) A polycyclic alkaloid whose pharmacological activity is similar to nicotine; used in the treatment of nicotinism.
n
(biochemistry) Any of a family of cytotoxic peptides found in marine ascidians of the genus Diazona.
n
(organic chemistry) A hydroxyanthrone anthracene derivative used as a medicine for skin affected by psoriasis.
n
(organic chemistry) Any of a group of oligocyclic lactones that are the basis of several antibiotics
n
(medicine) A derivative of podophyllotoxin that is used in the treatment of some cancers by inhibiting mitosis.
n
(organic chemistry) Any of a group of alkaloids present in marine tunicates of the genus Eudistoma
n
(organic chemistry) The compound (3-chloro-4-methylphenyl)[4-(4-nitrophenyl)-1-piperazinyl]-methanone that blocks biofilm formation
n
(organic chemistry) A C-nucleoside, (2S,3R,4S,5R)-2-(7-amino-2H-pyrazolo[4,3-d]pyrimidin-3-yl)-5-(hydroxymethyl)oxolane-3,4-diol, that inhibits the E. coli enzyme purine nucleoside phosphorylase
n
A meroterpenoid anthrafuran 2,3,11,11a-tetrahydroanthra[2,3-b]furan produced by Aspergillus fumigatus when treated with the actinomycete Streptomyces rapamycinicus
n
Alternative form of fumitremorgin [Any of a class of tremorogenic metabolites of Aspergillus and Penicillium.]
n
(biochemistry) A cyclopeptide composed of valine and phenylalanine residues
n
(medicine, organic chemistry) An antibiotic produced by the bacterium Burkholderia gladioli, with potential applications in treating tuberculosis.
n
(medicine) A daphnane diterpene that may have some anticancer activity
n
Alternative form of harmine [(organic chemistry) A fluorescent harmala alkaloid belonging to the carboline family of compounds, found in harmal and certain other plants.]
n
(pharmacology) A pentacyclic antibiotic 3,5,7,10-tetrahydroxy-1,1,9-trimethyl-2H-benzo(c,d)pyrene-2,6(1H)-dione.
n
(organic chemistry) An anticancer macrolide present in Streptomyces violaceoruber
n
Any of a group of metabolites of marine sponges, having possible applications in the treatment of cancer.
n
(organic chemistry) A polycyclic heterocycle present in some soil bacteria
n
A particular steroid glycoside.
n
(organic chemistry) Any of a particular group of angiogenesis inhibitors isolated from an actinomycete.
n
(organic chemistry) The anthraquinone derivative 1,7-dihydroxy-3-methoxy-6-methyl-9,10-anthraquinone that is a bioactive metabolite produced by a plant-pathogenic fungus of the genus Stemphylium (family Pleosporaceae, order Pleosporales)
n
(biochemistry) Any of a group of bicyclic peptides, produced by Aspergillus niger or close relatives, that are mycotoxins.
n
(biochemistry) A marine derived macrolide, a oxygen heterocyclic compound with a large ring.
n
(organic chemistry) A tricyclic depsipeptide isolated from the toxic cyanobacterium Microcystis viridis
n
A mainly cardiotoxic mycotoxin formed in many cereals by a number of Fusarium species.
n
(organic chemistry, medicine) Any of a group of pyranonaphthoquinone antibiotics and antifungal agents isolated from an actinomycete
n
A macrolide that has nine carbon atoms and one double bond in the lactone ring
n
(organic chemistry) Any of a class of cyclic lipopeptide lactones present in some Pseudomonas bacteria
n
Alternative form of phalloidin [(biochemistry) A toxic cyclic peptide obtained from the mushroom Amanita phalloides]
n
an antifungal drug used to treat ophthalmic infections, and as a food preservative
n
(medicine) Any of a family of macrocyclic lactones, isolated from Streptomyces platensis, that exhibit antitumor activity
n
(organic chemistry) Any of a group of macrolides, having a hemiacetal sidechain, that are used in the treatment of postmenopausal osteoporosis
n
(biochemistry) A toxic cyclic peptide obtained from the mushroom Amanita phalloides
n
(organic chemistry) A carcinogenic terpenoid glycoside, found in bracken, that is poisonous to cattle.
n
A stereoisomer of yohimbine with stimulant and aphrodisiac properties.
n
(organic chemistry) Any of a group of complex spiroketals, isolated from soil actinomycete of the genus Streptomyces, that have antibiotic activity and inhibit cell growth
n
(biochemistry) Any of a group of antifungal cyclic tetrapeptides present in a Rhodococcus
n
(organic chemistry) A polyene macrocyclic lactam present in an actinomycete associated with the mud dauber, Sceliphron caementarium
n
Synonym of serratamolide
n
(organic chemistry) Any of a group of polycyclic macrolides produced by the marine bacterium Salinispora tropica
n
Alternative form of staurosporine [(medicine) An alkaloid derived from the bacterium Streptomyces staurosporeus that has antifungal and antihypertensive properties]
n
The mycotoxin 5S,6S-3-acetyl-5-sec-butyl-4-hydroxypyrrolidone-2,4-dione, soluble in chloroform and methanol, that inhibits protein synthesis.
n
(organic chemistry) A toxin, methyl 4,5'-dimethoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate, produced by Aspergillus fumigatus.
n
(organic chemistry) Any of a group of macrolide spiroketals, present in some bacteria, that possess immunosuppressant activity
n
(organic chemistry) A particular antibiotic macrolactam
n
(pharmacology) A particular semisynthetic vinca alkaloid with antitumour activity.
n
(organic chemistry, medicine) An antibiotic, obtained from Streptomyces viridochromogenes, that has a complex structure including a cyclopentene ring
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