A mission control center (MCC, sometimes called a flight control center or operations center) is a facility that manages space flights, usually from the point of launch until landing or the end of the mission.

NASA's Christopher C. Kraft Jr. Mission Control Center (MCC-H, initially called Integrated Mission Control Center, or IMCC), also known by its radio callsign, Houston, is the facility at the Lyndon B. Johnson Space Center in Houston, Texas, that manages flight control for the United States human space program, currently involving astronauts aboard the International Space Station.

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The RKA Mission Control CenterRKA: Russian space agency, also known by its acronym TsUP or by its radio callsign Mission Control Moscow, is the mission control center of Roscosmos.