The James R. Thompson Center, under reconstruction as Google Center or Googleplex Chicago and originally the State of Illinois Center, is a postmodern-style building designed by architect Helmut Jahn, located at 100 W. Randolph Street in the Loop district of Chicago.

Floyd James "Jim" Thompson (July 8, 1933 – July 16, 2002) was a United States Army colonel.

James Robert Thompson (June 18, 1938 – December 4, 2017) was an American mathematician, statistician, and university professor whose most influential work combined applied mathematics and nonparametric statistics with computing technologies to advance the fields of financial engineering and computational finance, model disease progression, assess problems in public health, and optimize quality control in industrial manufacturing.

James David Thompson (January 11, 1920 in Indianapolis – September 1, 1973) was an American sociologist.