The hallmarks of cancer were originally six biological capabilities acquired during the multistep development of human tumors and have since been increased to eight capabilities and two enabling capabilities.

A silver object that is to be sold commercially is, in most countries, stamped with one or more silver hallmarks indicating the purity of the silver, the mark of the manufacturer or silversmith, and other (optional) markings to indicate the date of manufacture and additional information about the piece.

Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death.