Juan Valentin Furagganan Ponce Enrile Sr., (born Juan Valentin Furagganan; February 14, 1924), also referred to by his initials JPE, is a Filipino politician and lawyer who served as 21st President of the Senate of the Philippines from 2008 to 2013 and known for his role in the administration of Philippine president Ferdinand Marcos; his role in the failed coup that helped hasten the 1986 People Power Revolution and the ouster of Marcos; and his tenure in the Philippine legislature in the years after the revolution.

Juan Castañer Ponce Enrile Jr. (born July 16, 1958), also known as Jack Enrile or JPEJ, is a Filipino politician.

Arturo "Boy" Tiongson Enrile (June 20, 1940 – January 14, 1998) was the Secretary of the Department of Transportation and Communications from 1997 to 1998.

Salvacion "Sally" Ponce-Enrile (née Santiago; born March 12, 1970) is a Filipino politician and wife of former Congressman Jack Enrile of the 1st District of Cagayan.