The word "splenetic" has been employed in literature to evoke a sense of irritable, bitter humor and to metaphorically denote a sour or acerbic temperament. For instance, Santayana [1] uses it to characterize a pernicious form of religion, while Hume [2] and Carlyle [3, 4, 5] apply it to describe moods and characters dominated by a cantankerous spirit—one that is as much a physical disposition, as in Molière's reference to the spleen in [6], as it is an emotional state. Rabelais [7] even weaves it into lists that underscore its almost tangible presence, and Shelley [8] contrasts its dour implications with the restorative nature of good humor. Together, these examples illustrate how “splenetic” transcends its anatomical roots to embody a broader critique of mordant and satirical dispositions in literature.