The word “extremity” displays a remarkable flexibility in literature, serving both literal and metaphorical functions. In scientific and anatomical contexts, authors use it to denote the physical end or tip of a structure—for example, referring to parts of the stomach or the tail of an animal ([1], [2], [3]). In geographical and spatial descriptions, “extremity” marks boundaries or remote endpoints, as seen in the detailed measurements and locations in the Journals of Lewis and Clark ([4], [5], [6]). The term also takes on metaphorical weight, capturing moments of intense distress or critical turning points, such as in portrayals of emotional suffering or last stands in battle ([7], [8], [9]). Even when used in everyday language or technical descriptions, “extremity” subtly communicates the idea of an ultimate limit—whether it be the final part of a physical form or the most severe point of a situation ([10], [11]).