Usually means: Antidepressants that increase serotonin levels.
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We found 10 dictionaries that define the word SSRIs:

General (6 matching dictionaries)
  1. SSRIs: Merriam-Webster
  2. SSRIS: Vocabulary.com
  3. SSRIs: Wiktionary
  4. SSRIs: Dictionary.com
  5. SSRIs: Wikipedia, the Free Encyclopedia
  6. SSRIs: TheFreeDictionary.com

Medicine (4 matching dictionaries)
  1. SSRIs: Merriam-Webster Medical Dictionary
  2. Multiple Sclerosis Encyclopaedia (No longer online)
  3. SSRIs: Medical dictionary
  4. WeMove Glossary of Terms (No longer online)

(Note: See ssri as well.)

Definitions from Wiktionary (SSRI)

noun:  (medicine) Initialism of selective serotonin reuptake inhibitor. [(pharmacology) Any of a class of drugs, such as fluoxetine or sertraline, that inhibit the uptake of serotonin in the central nervous system and are often used to treat certain mental illnesses, such as depression.]
noun:  (medicine) Initialism of serotonin-specific reuptake inhibitor. [(pharmacology) A selective serotonin reuptake inhibitor.]
▸ Also see ssri


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