Usually means: Helper molecule for enzyme activity.
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We found 27 dictionaries that define the word cofactor:

General (15 matching dictionaries)
  1. cofactor: Merriam-Webster
  2. cofactor: Oxford Learner's Dictionaries
  3. cofactor: American Heritage Dictionary of the English Language
  4. cofactor: Collins English Dictionary
  5. cofactor: Vocabulary.com
  6. cofactor: Wordnik
  7. cofactor: Wiktionary
  8. cofactor: Webster's New World College Dictionary, 4th Ed.
  9. cofactor: Infoplease Dictionary
  10. cofactor: Dictionary.com
  11. Cofactor (biochemistry), Cofactor (linear algebra), Cofactor: Wikipedia, the Free Encyclopedia
  12. cofactor: Rhymezone
  13. cofactor: FreeDictionary.org
  14. cofactor: Mnemonic Dictionary
  15. cofactor: TheFreeDictionary.com

Computing (1 matching dictionary)
  1. cofactor: Encyclopedia

Medicine (7 matching dictionaries)
  1. cofactor: Merriam-Webster Medical Dictionary
  2. Dorland's Illustrated Medical Dictionary (No longer online)
  3. online medical dictionary (No longer online)
  4. Hepatitis C Information Central (No longer online)
  5. AIDS Medical Glossary and Drug Chart (No longer online)
  6. Glossary of HIV/AIDS Related Terms (No longer online)
  7. cofactor: Medical dictionary

Science (4 matching dictionaries)
  1. Drug Discovery and Development (No longer online)
  2. Cofactor: Eric Weisstein's World of Mathematics
  3. cofactor, cofactor: PlanetMath Encyclopedia
  4. AGRICULTURAL AND ENVIRONMENTAL BIOTECHNOLOGY (No longer online)

(Note: See cofactors as well.)

Definitions from Wiktionary (cofactor)

noun:  A contributing factor.
noun:  (biochemistry) A substance, especially a coenzyme or a metal, that must be present for an enzyme to function.
noun:  (biochemistry) A molecule that binds to and regulates the activity of a protein.
noun:  (mathematics) The result of a number being divided by one of its factors.
noun:  (mathematics, linear algebra, of a matrix) The signed determinant of the submatrix produced by removing the row and column containing a specified element; primarily used in the recursive definition and calculation of the determinant of a matrix.

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