Usually means: Become stronger in adversity, resilience.
Definitions Related words Mentions
We found 3 dictionaries that define the word toughen up:

General (2 matching dictionaries)
  1. toughen up: Wiktionary
  2. toughen up: TheFreeDictionary.com

Miscellaneous (1 matching dictionary)
  1. toughen up: Idioms

Definitions from Wiktionary (toughen up)

verb:  (idiomatic, ambitransitive) To make or become mentally tougher.

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