Usually means: Tremors caused by fear, cold.
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We found 24 dictionaries that define the word shakes:

General (14 matching dictionaries)
  1. shakes, the shakes: Merriam-Webster
  2. the shakes: Oxford Learner's Dictionaries
  3. shakes, the shakes: Collins English Dictionary
  4. shakes: Vocabulary.com
  5. Shake's, Shakes, shakes, the shakes: Wordnik
  6. shakes, the shakes: Cambridge Advanced Learner's Dictionary
  7. Shakes, shakes: Wiktionary
  8. Shakes, The shakes, shakes: Dictionary.com
  9. shakes: Cambridge Essential American English Dictionary
  10. Shakes (Tlingit leaders), Shakes (timber), Shakes (wood), Shakes, The Shakes (Herbert album), The shakes: Wikipedia, the Free Encyclopedia
  11. THE SHAKES: Dictionary of Americanisms (1848)
  12. Shakes: Dictionary of Phrase and Fable (1898)
  13. the shakes: FreeDictionary.org
  14. The shakes, shakes: TheFreeDictionary.com

Business (1 matching dictionary)
  1. The shakes, shakes: Legal dictionary

Computing (1 matching dictionary)
  1. The shakes, shakes: Encyclopedia

Medicine (4 matching dictionaries)
  1. shakes: Merriam-Webster Medical Dictionary
  2. online medical dictionary (No longer online)
  3. The shakes, shakes: Medical dictionary
  4. Rudy's List of Archaic Medical Terms (No longer online)

Miscellaneous (2 matching dictionaries)
  1. Shakes, Shakes, Shakes: Terminology and Descriptions of Geneaological Words
  2. shakes: Idioms

Slang (2 matching dictionaries)
  1. shakes: Green’s Dictionary of Slang
  2. shakes, the shakes: Urban Dictionary

(Note: See shake as well.)

Definitions from Wiktionary (shakes)

noun:  (plural only) A pattern of behavior including twitches, tics and spasms typical of withdrawal from addiction; usually following the.
noun:  (informal) A fit of trembling or shivering.

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