Usually means: Contagious disease causing skin eruptions.
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We found 39 dictionaries that define the word pox:

General (25 matching dictionaries)
  1. pox: Longman Dictionary of Contemporary English
  2. pox: Merriam-Webster
  3. pox, the pox: Oxford Learner's Dictionaries
  4. pox: American Heritage Dictionary of the English Language
  5. pox, the pox: Collins English Dictionary
  6. pox: Vocabulary.com
  7. Pox, pox: Wordnik
  8. the pox: Cambridge Advanced Learner's Dictionary
  9. pox: Wiktionary
  10. pox: Webster's New World College Dictionary, 4th Ed.
  11. pox: The Wordsmyth English Dictionary-Thesaurus
  12. pox: Infoplease Dictionary
  13. pox: Dictionary.com
  14. pox: Online Etymology Dictionary
  15. Pox (drink), Pox, The P.O.X: Wikipedia, the Free Encyclopedia
  16. Pox: Online Plain Text English Dictionary
  17. pox: Webster's Revised Unabridged, 1913 Edition
  18. pox: Rhymezone
  19. pox: AllWords.com Multi-Lingual Dictionary
  20. pox: Webster's 1828 Dictionary
  21. pox: FreeDictionary.org
  22. pox: Mnemonic Dictionary
  23. pox: TheFreeDictionary.com

Computing (1 matching dictionary)
  1. pox: Encyclopedia

Medicine (6 matching dictionaries)
  1. pox: Merriam-Webster Medical Dictionary
  2. Dorland's Illustrated Medical Dictionary (No longer online)
  3. online medical dictionary (No longer online)
  4. Probert Encyclopaedia of Medicine (No longer online)
  5. pox: Medical dictionary
  6. Rudy's List of Archaic Medical Terms (No longer online)

Miscellaneous (4 matching dictionaries)
  1. POX: Acronym Finder
  2. POX: Three Letter Words with definitions
  3. AbbreviationZ (No longer online)
  4. pox: Idioms

Slang (3 matching dictionaries)
  1. pox, pox, pox: Green’s Dictionary of Slang
  2. Pox: Street Terms: Drugs and the Drug Trade
  3. Pox: Urban Dictionary

(Note: See poxes as well.)

Definitions from Wiktionary (
)
American English Definition British English Definition
noun:  A disease characterized by purulent skin eruptions that may leave pockmarks.
noun:  Syphilis.
noun:  (figurative) A curse.
verb:  (transitive, dated) To infect with the pox, or syphilis.

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