Usually means: Institution for treating mental illness.
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We found 18 dictionaries that define the word nuthouse:

General (15 matching dictionaries)
  1. nuthouse: Longman Dictionary of Contemporary English
  2. nuthouse: Merriam-Webster
  3. nuthouse: Oxford Learner's Dictionaries
  4. nuthouse: Collins English Dictionary
  5. nuthouse: Vocabulary.com
  6. Nuthouse, nuthouse: Wordnik
  7. nuthouse: Cambridge Advanced Learner's Dictionary
  8. nuthouse: Wiktionary
  9. nuthouse: Webster's New World College Dictionary, 4th Ed.
  10. nuthouse: Dictionary.com
  11. Nuthouse (album), The Nuthouse (film): Wikipedia, the Free Encyclopedia
  12. nuthouse: FreeDictionary.org
  13. nuthouse: Mnemonic Dictionary
  14. nuthouse: TheFreeDictionary.com
  15. Nuthouse: Rhymezone

Business (1 matching dictionary)
  1. nuthouse: Legal dictionary

Computing (1 matching dictionary)
  1. nuthouse: Encyclopedia

Medicine (1 matching dictionary)
  1. nuthouse: Medical dictionary

(Note: See nuthouses as well.)

Definitions from Wiktionary (nuthouse)

noun:  (informal, offensive) A hospital for the mentally ill.

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