Usually means: Extra tooth between upper incisors.
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We found 4 dictionaries that define the word mesiodens:

General (2 matching dictionaries)
  1. mesiodens: Wiktionary
  2. mesiodens: Dictionary.com

Medicine (2 matching dictionaries)
  1. online medical dictionary (No longer online)
  2. mesiodens: Medical dictionary

Definitions from Wiktionary (mesiodens)

noun:  A supernumerary malformed, peg-like tooth occurring between the maxillary central incisors.

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