Usually means: Sponge-like fruit used for scrubbing.
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We found 17 dictionaries that define the word luffa:

General (15 matching dictionaries)
  1. luffa: Merriam-Webster
  2. luffa: Oxford Learner's Dictionaries
  3. luffa: American Heritage Dictionary of the English Language
  4. luffa: Collins English Dictionary
  5. luffa: Vocabulary.com
  6. Luffa, luffa: Wordnik
  7. luffa: Wiktionary
  8. luffa: Webster's New World College Dictionary, 4th Ed.
  9. luffa: Infoplease Dictionary
  10. Luffa, luffa: Dictionary.com
  11. Luffa: Wikipedia, the Free Encyclopedia
  12. luffa: Rhymezone
  13. luffa: FreeDictionary.org
  14. luffa: Mnemonic Dictionary
  15. luffa: TheFreeDictionary.com

Computing (1 matching dictionary)
  1. luffa: Encyclopedia

Medicine (1 matching dictionary)
  1. Medical Dictionary (No longer online)

(Note: See luffas as well.)

Definitions from Wiktionary (Luffa)

noun:  Alternative spelling of loofah [Any of several tropical vines of the genus Luffa, having almost cylindrical fruit with a spongy, fibrous interior; the dishcloth gourd.]

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