Usually means: Sexually transmitted disease, specifically syphilis.
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We found 24 dictionaries that define the word lues:

General (16 matching dictionaries)
  1. lues: Merriam-Webster
  2. lues: Oxford Learner's Dictionaries
  3. lues: American Heritage Dictionary of the English Language
  4. lues: Collins English Dictionary
  5. lues: Vocabulary.com
  6. Lues, lues: Wordnik
  7. Lues, lues: Wiktionary
  8. lues: Webster's New World College Dictionary, 4th Ed.
  9. lues: Infoplease Dictionary
  10. lues: Dictionary.com
  11. Lues: Online Plain Text English Dictionary
  12. lues: Webster's Revised Unabridged, 1913 Edition
  13. Lues: AllWords.com Multi-Lingual Dictionary
  14. lues: FreeDictionary.org
  15. lues: Mnemonic Dictionary
  16. lues: TheFreeDictionary.com

Computing (1 matching dictionary)
  1. lues: Encyclopedia

Medicine (7 matching dictionaries)
  1. lues: Merriam-Webster Medical Dictionary
  2. Lues: MedTerms.com Medical Dictionary
  3. online medical dictionary (No longer online)
  4. lues: Medical dictionary
  5. Rudy's List of Archaic Medical Terms (No longer online)
  6. University of Maryland Glossary of Medical Terms (No longer online)
  7. Lues: Drug Medical Dictionary

(Note: See luetic as well.)

Definitions from Wiktionary (lues)

noun:  (dated, medicine) A plague or disease, especially syphilis.

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