Usually means: Restrained with wrists locked together.
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We found 15 dictionaries that define the word handcuffed:

General (12 matching dictionaries)
  1. handcuffed: Merriam-Webster
  2. handcuffed: Collins English Dictionary
  3. handcuffed: Vocabulary.com
  4. Handcuffed, handcuffed: Wordnik
  5. handcuffed: Cambridge Advanced Learner's Dictionary
  6. handcuffed: Wiktionary
  7. Handcuffed, handcuffed: Dictionary.com
  8. handcuffed: Cambridge Essential American English Dictionary
  9. Handcuffed: Online Plain Text English Dictionary
  10. Handcuffed: AllWords.com Multi-Lingual Dictionary
  11. handcuffed: FreeDictionary.org
  12. handcuffed: TheFreeDictionary.com

Business (1 matching dictionary)
  1. handcuffed: Legal dictionary

Computing (1 matching dictionary)
  1. handcuffed: Encyclopedia

Slang (1 matching dictionary)
  1. handcuffed: Urban Dictionary

(Note: See handcuff as well.)

Definitions from Wiktionary (handcuff)

noun:  (rarely singular) One ring of a locking fetter for the hand or one pair.
verb:  (transitive) To apply handcuffs to someone.
verb:  (transitive, figuratively) to restrain or restrict.
▸ Also see handcuff


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