Usually means: Removal of testicles or ovaries.
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We found 39 dictionaries that define the word castration:

General (20 matching dictionaries)
  1. castration: Merriam-Webster
  2. castration: Oxford Learner's Dictionaries
  3. castration: Collins English Dictionary
  4. castration: Vocabulary.com
  5. Castration, castration: Wordnik
  6. castration: Cambridge Advanced Learner's Dictionary
  7. castration: Wiktionary
  8. Castration, castration: Dictionary.com
  9. castration: Online Etymology Dictionary
  10. Castration: Wikipedia, the Free Encyclopedia
  11. Castration: Online Plain Text English Dictionary
  12. castration: Webster's Revised Unabridged, 1913 Edition
  13. castration: Rhymezone
  14. Castration: AllWords.com Multi-Lingual Dictionary
  15. castration: Webster's 1828 Dictionary
  16. castration: FreeDictionary.org
  17. castration: Mnemonic Dictionary
  18. castration: TheFreeDictionary.com

Business (2 matching dictionaries)
  1. THE 'LECTRIC LAW LIBRARY'S REFERENCE ROOM (No longer online)
  2. Bouvier's Law Dictionary 1856 Edition (No longer online)

Computing (1 matching dictionary)
  1. castration: Encyclopedia

Medicine (10 matching dictionaries)
  1. castration: Merriam-Webster Medical Dictionary
  2. Dorland's Illustrated Medical Dictionary (No longer online)
  3. Castration: MedTerms.com Medical Dictionary
  4. Medical Dictionary (No longer online)
  5. Breast Cancer Talking Dictionary (No longer online)
  6. online medical dictionary (No longer online)
  7. castration: Dictionary of Cancer Terms
  8. castration: Medical dictionary
  9. Castration: Drug Medical Dictionary
  10. Hyperdictionary (No longer online)

Miscellaneous (2 matching dictionaries)
  1. Brilliant Dream Dictionary (No longer online)
  2. Glossary of Unusual Sexual Practices (No longer online)

Science (1 matching dictionary)
  1. Agricultural Thesaurus and Glossary (No longer online)

Slang (1 matching dictionary)
  1. Castration: Urban Dictionary

Sports (1 matching dictionary)
  1. Cat Terms (No longer online)

Tech (1 matching dictionary)
  1. Washington State Definitions and Abbreviations of Vetrinary Terms (No longer online)

(Note: See castrate as well.)

Definitions from Wiktionary (castration)

noun:  (surgery) The act of removing the testicles.
noun:  (figuratively) Any act that removes power from a person (particularly a man) or entity.

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