Usually means: Security protocol for encrypted communication.
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We found 20 dictionaries that define the word TLS:

General (8 matching dictionaries)
  1. tls: Longman Dictionary of Contemporary English
  2. TLS: Collins English Dictionary
  3. TL's, TLs, tls: Wordnik
  4. TLs: Wiktionary
  5. TLS: Dictionary.com
  6. TLS (disambiguation), TLS, Tls: Wikipedia, the Free Encyclopedia
  7. TLS: Stammtisch Beau Fleuve Acronyms
  8. TLS: TheFreeDictionary.com

Art (1 matching dictionary)
  1. ODLIS: Online Dictionary of Library and Information Science (No longer online)

Computing (6 matching dictionaries)
  1. TLS: Free On-line Dictionary of Computing
  2. TLS (Transport Layer Security): Linktionary Networking Glossary
  3. Webopedia (No longer online)
  4. TLS: Hacking Lexicon
  5. Data Formats and Their Sugggested File Extensions (No longer online)
  6. TLS: Encyclopedia

Medicine (1 matching dictionary)
  1. online medical dictionary (No longer online)

Miscellaneous (2 matching dictionaries)
  1. TLS: Acronym Finder
  2. AbbreviationZ (No longer online)

Science (1 matching dictionary)
  1. TLS: A Dictionary of Quaternary Acronyms and Abbreviations

Slang (1 matching dictionary)
  1. TLS: Urban Dictionary

Definitions from Wiktionary (TLS)

noun:  Initialism of tumor lysis syndrome.
noun:  (Internet, security) Initialism of Transport Layer Security.

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