Usually means: Operating while intoxicated; legal term.
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We found 10 dictionaries that define the word OWI:

General (6 matching dictionaries)
  1. Owi, owi: Wordnik
  2. OWI: Wiktionary
  3. OWI: Infoplease Dictionary
  4. OWI: Dictionary.com
  5. OWI: Wikipedia, the Free Encyclopedia
  6. OWI: Stammtisch Beau Fleuve Acronyms

Computing (1 matching dictionary)
  1. OWI: Encyclopedia

Miscellaneous (2 matching dictionaries)
  1. OWI: Acronym Finder
  2. AbbreviationZ (No longer online)

Slang (1 matching dictionary)
  1. owi: Urban Dictionary

Definitions from Wiktionary (OWI)

noun:  Initialism of operating (a motor vehicle) while impaired/intoxicated. [(uncountable) Synonym of operation (in the uncountable sense).]
noun:  (US, World War II) Initialism of Office of War Information.

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