Usually means: Restroom, toilet, especially in Britain.
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We found 18 dictionaries that define the word Lou:

General (9 matching dictionaries)
  1. lou: Collins English Dictionary
  2. Lou, lou: Wordnik
  3. Lou: Wiktionary
  4. Lou: Infoplease Dictionary
  5. lou: Dictionary.com
  6. LOU, Lou (French singer), Lou (given name), Lou (singer), Lou, Lou: Wikipedia, the Free Encyclopedia
  7. Lou: Rhymezone
  8. Lou: Stammtisch Beau Fleuve Acronyms
  9. lou: TheFreeDictionary.com

Computing (2 matching dictionaries)
  1. LOU: Netlingo
  2. Lou: Encyclopedia

Miscellaneous (4 matching dictionaries)
  1. baby names list (No longer online)
  2. LOU: Acronym Finder
  3. LOU: Three Letter Words with definitions
  4. AbbreviationZ (No longer online)

Slang (3 matching dictionaries)
  1. lou, lou, lou: Green’s Dictionary of Slang
  2. Totally Unofficial Rap (No longer online)
  3. Lou, The 'Lou, The Lou: Urban Dictionary

Definitions from Wiktionary (Lou)

noun:  (countable) A unisex given name.
noun:  A diminutive of the male given name Louis.
noun:  A diminutive of the female given names Louisa or Louise; often also used as a middle name.
noun:  (with definite article) A nickname for St. Louis. A city in Missouri, United States
noun:  A Southeast Admiralty Islands language spoken on Lou Island of Manus Province, Papua New Guinea.
noun:  The Torricelli language of Papua New Guinea.

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loo

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