Usually means: Large, gentle dog breed, imposing.
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We found 20 dictionaries that define the word Great Dane:

General (17 matching dictionaries)
  1. Great Dane: Merriam-Webster
  2. Great Dane: Oxford Learner's Dictionaries
  3. Great Dane: American Heritage Dictionary of the English Language
  4. Great Dane: Collins English Dictionary
  5. Great Dane: Vocabulary.com
  6. Great Dane: Wordnik
  7. Great Dane: Wiktionary
  8. Great Dane: The Wordsmyth English Dictionary-Thesaurus
  9. Great Dane: Infoplease Dictionary
  10. Great Dane, great dane: Dictionary.com
  11. Great Dane, Great dane, The Great Dane: Wikipedia, the Free Encyclopedia
  12. Great dane: Rhymezone
  13. great dane: FreeDictionary.org
  14. great dane: Mnemonic Dictionary
  15. Great Dane: TheFreeDictionary.com
  16. great dane: Longman Dictionary of Contemporary English
  17. Great Dane: Merriam-Webster

Computing (1 matching dictionary)
  1. Great Dane: Encyclopedia

Medicine (1 matching dictionary)
  1. Great Dane: Medical dictionary

Slang (1 matching dictionary)
  1. Great Dane: Urban Dictionary

(Note: See great_danes as well.)

Definitions from Wiktionary (Great Dane)

noun:  A mastiff known for its great size, bred in Germany to hunt boar and large game.

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