Usually means: Weariness or dissatisfaction with life.
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We found 9 dictionaries that define the word taedium vitae:

General (7 matching dictionaries)
  1. taedium vitae: Merriam-Webster
  2. taedium vitae: Oxford Learner's Dictionaries
  3. taedium vitae: Collins English Dictionary
  4. taedium vitae: Wiktionary
  5. taedium vitae: The Wordsmyth English Dictionary-Thesaurus
  6. taedium vitae: Dictionary.com
  7. taedium vitae: TheFreeDictionary.com

Medicine (1 matching dictionary)
  1. taedium vitae: Merriam-Webster Medical Dictionary

Slang (1 matching dictionary)
  1. taedium-vitae: Urban Dictionary

Definitions from Wiktionary (taedium vitae)

noun:  Profound ennui or weariness of one's life.

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