Usually means: Twisting of DNA beyond helical.
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We found 8 dictionaries that define the word supercoiling:

General (4 matching dictionaries)
  1. supercoiling: Merriam-Webster
  2. supercoiling: Wiktionary
  3. supercoiling: Dictionary.com
  4. Supercoiling: Wikipedia, the Free Encyclopedia

Computing (1 matching dictionary)
  1. supercoiling: Encyclopedia

Medicine (3 matching dictionaries)
  1. supercoiling: Merriam-Webster Medical Dictionary
  2. online medical dictionary (No longer online)
  3. supercoiling: Medical dictionary

Definitions from Wiktionary (supercoiling)

noun:  (genetics) The coiling of the DNA helix upon itself, which can disrupt transcription and lead to cell death.

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