Usually means: Chemical introduction of sulfonyl group.
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We found 7 dictionaries that define the word sulphonation:

General (4 matching dictionaries)
  1. sulphonation: Collins English Dictionary
  2. sulphonation: Wordnik
  3. sulphonation: Wiktionary
  4. Sulphonation: TheFreeDictionary.com

Computing (1 matching dictionary)
  1. Sulphonation: Encyclopedia

Medicine (2 matching dictionaries)
  1. sulphonation: Merriam-Webster Medical Dictionary
  2. Sulphonation: Medical dictionary

Definitions from Wiktionary (Sulphonation)

noun:  Alternative spelling of sulfonation [(chemistry) The replacement of a hydrogen atom of an organic compound with a sulfonic acid (-SO₃H) functional group, often by reaction with sulfuric acid at high temperatures]

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