Usually means: Birthmark with speckled or spotted appearance.
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We found 4 dictionaries that define the word spilus:

General (3 matching dictionaries)
  1. spilus: Wordnik
  2. spilus: Wiktionary
  3. spilus: Dictionary.com

Medicine (1 matching dictionary)
  1. online medical dictionary (No longer online)

Definitions from Wiktionary (spilus)

noun:  naevus

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